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Figure Caption
Fig. 6 D2 accumulation is necessary to drive Bort-induced axonopathy. (A) Representative IF images of neurofilament staining in DRG neurons silenced of CCP1 expression at 5 DIV and treated at 12 DIV with 100 nM of Bort for 24 h. Scale bar, 50 μm. (B) Axonal degeneration in DRG neurons treated as in A. Data are from at least 6 to 12 fields per condition (n = 4 experiments). Data are shown as medians plus interquartile range, and statistics were analyzed by Mann–Whitney U test. *P < 0.05.
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