Figure 2
Morphometric analysis of hsd11b2 mutant zebrafish line. (A) Measurements of body length, eye diameter and eye area of 6-dpf hsd11b2+/+, hsd11b2+/− and hsd11b2−/− larvae. (B) Measurements of body length, eye diameter and eye area of 15-dpf hsd11b2+/+, hsd11b2+/− and hsd11b2−/− larvae. (C) Measurements of body length of 3-mpf hsd11b2+/+, hsd11b2+/− and hsd11b2−/− fish. (D) Survival of hsd11b2+/+, hsd11b2+/− and hsd11b2−/− animals at 5, 6, 15 and 60 dpf. Mean ± SEM. significant. Student’s t-test was used to evaluate the morphometric differences and X2 test was used to evaluate the differences of genotype distribution compared to the expected ratios. * p < 0.05; ** p < 0.01; ns = not significant.