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Fig. 4
The absence of the pacemaker ring in isl1 mutant causes the loss of expression of fhf2, hcn4, bmp4. A–H Expression pattern (labeled with arrow) of fhf2a (A, B), bmp4 (C, D), hcn4 (E, F) and EGFP (G, H) in isl1 siblings and mutants. (A–F) WISH, (G, H) confocal microscopy of CCS in the sibling and isl1 mutant
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