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Fig 6
qPCR graph of mtDNA amount from wildtype (Wildtype, black circles) and aldh7a1 homozygous knock-out (aldh7a1 knock-out, grey squares) zebrafish embryos, demonstrating only a slight reduction in mtDNA copy number in knock-out relative to the wildtype embryos. Each dot represents DNA extracted from 5 embryos. The amounts of mtDNA from knock-out and wildtype embryos were normalized to the average mtDNA amount from the wildtype embryos. p value is calculated by an unpaired two-tailed student t-test. Error bars, mean and SD.
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