mRNA-transcription factor (TF) interactions across FRCs according to experimentally validated predictions. (A) FRC-mRNA-TF regulatory network based on TFmiR gene-TF interactions. FRCs, TFs. (black nodes with white text)-TFs that were differentially expressed across 5 or more FRCs, with larger nodes denoting higher number of FRCs. (B) Heatmap representing fold changes of selected TFs across all FRCs. Both zebrafish and human orthologs are provided. (C) Heatmap representing mRNA-TF combinations that were co-altered across multiple FRCs. Numbers within cells represent number of FRCs that a specific pair was altered in. Red arrows represent the FRCs for specific pairs that are discussed in the manuscript. All data based on TFmiR experimentally validated predictions.
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