Figure 7

Figure 7

Hypothetical model explaining the effects of Stag1a and Stag2b loss on primitive erythropoiesis. In stag1a^nz204 mutants, an expansion of early haematopoietic progenitors driven by increased scl expression may lead to precocious differentiation that exhausts the progenitor pool. In stag2b^nz207 mutants, a limited pool of haematopoietic progenitors resulting from reduced scl expression leads to a reduction in primitive erythropoiesis.