ZFIN Image: Whittle et al., 2020, Figure EV3

Image

Figure Caption

Figure EV3 Representative examples of each embryonic and adult graded phenotype

A

Grading scale for 2 dpf embryos. Normal is classified as 0 visible abnormalities, mild is classified as 1 notochord curve or kink, moderate is classified as multiple notochord curves or kinks, and severe is classified as multiple notochord kinks that severely distort the body. Arrowheads indicate notochord abnormalities.

B

Grading scale for adult skeletal abnormalities. Normal is classified as 0 visible abnormalities, mild is classified as 1 spinal curve or kink, moderate is classified as multiple spinal curves or kinks, or apparent vertebral fusion, and severe is classified as multiple spinal kinks or vertebral fusions that severely distort the body. Arrowheads indicate spinal abnormalities.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Mol. Med.