ZFIN Image: Spinazzola et al., 2020, Fig. 3.

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Figure Caption

Fig. 3.

Short-term assay of SSRIs. (A–F) Treatment with citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine and sertraline did not significantly decrease the percentage of zebrafish exhibiting the affected muscle phenotype detected by birefringence. Treatment with 2.5 μg/ml aminophylline significantly decreased the percentage of affected fish. (G) Zebrafish treated with fluoxetine exhibited dose-dependent toxicity. Data represent means±s.e.m.; *P<0.05 versus paired control by one-way ANOVA and Bonferroni post-hoc test. Values above each column indicate the number of sapje (N) and sapje-like (n) fish treated with the respective drug.

Acknowledgments

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