ZFIN Image: Izarzugaza et al., 2020, Fig. 4

Image

Figure Caption

Fig. 4

Distribution of MPC and CADD scores of rare variants in 714 CHD cases and 4922 controls. Protein altering and truncating variants (PAV and PTV) with MAF < 0.001 identified in the genes ADCY2, ADCY5, CACNA1D, CACNA1H, CACNA1I, CACNA1S, GRIA4, ITPR1, NFAT5, and PLCB2 were scored using MPC score [22] (a) or CADD score [21] (b). N_CHD = 136 variants. N_Controls = 982 variants. Difference between median values of controls and cases was determined using a Mann-Whitney rank-sum test. **p < 0.01, *p < 0.05

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genome Med.