ZFIN Image: Liu et al., 2020, FIGURE 2

Image

Figure Caption

FIGURE 2

Morphological defects in the miR-430-deficient embryos. (A–O) The morphology of WT and miR-430-deficient embryos. The phenotypes are fully penetrant. Formation of the germ ring (black arrows) and shield (white arrows) were delayed in the miR-430^–/– mutants (A,B,F,G). The yolk was not enclosed by epiboly in the mutant at 9 hpf (C,H). The extension of the anterior-posterior body axis was reduced in the miR-430 mutants (D,E,I,J). The miR-430 mutants had no brain vesicles and lacked heart tissue and circulation (K,M). Tail blisters were observed in the mutant at 48 hpf (L,N). The miR-430 mimics but not the mismatched miR-430 with 2-nucleotide alterations could rescue the defects observed in the miR-430 mutants (O,P). The ratios of observed phenotypes were indicated.

Figure Data

Phenotype details

Acknowledgments

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