Figure 2

Figure 2

Grna; Grnb-deficient microglial cells display morphological changes associated with aging. (a–d) Micrographs depicting 4C4⁺ microglial cells. (a′–d′) Magnifications of boxed areas in (a–d), respectively. (a″–d″) Morphological tracing of 4C4⁺ microglial cells. Scale bars: 100 µm (a–d magnification) and 20 µm (a′–d′). (e–g) Morphological analysis depicting the average process length (e), number of main processes (f) and area of somata (g) of 4C4⁺ microglial cells. n.s, not significant, * p ≤ 0.05, **** p ≤ 0.0001, each data point represents a single cell (a total of 80 cells from four telencephali were analysed in each group).