ZFIN Image: Vetrivel et al., 2019, Fig. 7

Image

Figure Caption

Fig. 7

GJA8 in early eye development. The immunohistochemical distribution of GJA8 is shown at E11.5-E12.5 in wild type, Aey69 mutant and similar microphthalmic mouse model aphakia. The shrinking lens region is marked in the mutant models by white arrows. No obvious immunohistochemical localization of Gja8 in the mutant eyes at the stages of E11.5-E12.5 was observed. The bars indicate 100 μm; n = 3 for each embryonic stage; L, lens; R, retina; ON, optic nerve.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Experimental Eye Research, 188, Vetrivel, S., Tiso, N., Kügler, A., Irmler, M., Horsch, M., Beckers, J., Hladik, D., Giesert, F., Gailus-Durner, V., Fuchs, H., Sabrautzki, S., German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, Neuherberg, Germany, Adler, T., Treise, I., Busch, D.H., Aguilar-Pimentel, A., Ollert, M., Götz, A., Amarie, O.V., Stoeger, T., Schulz, H., Becker, L., Klopstock, T., Schrewe, A., Spielmann, N., Bekeredjian, R., Garrett, L., Hölter, S.M., Zimprich, A., Wurst, W., Mayer-Kuckuk, P., Hans, W., Rozman, J., Klingenspor, M., Neff, F., da Silva-Buttkus, P., Calzada-Wack, J., Rácz, I., Zimmer, A., Rathkolb, B., Wolf, E., Prehn, C., Adamski, J., Östereicher, M., Miller, G., Steinkamp, R., Lengger, C., Maier, H., Stoeger, C., Leuchtenberger, S., Gailus-Durner, V., Fuchs, H., Hrabě de Angelis, M., Hrabě de Angelis, M., Graw, J., Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia, 107632, Copyright (2019) with permission from Elsevier. Full text @ Exp. Eye. Res.