IMAGE

Fig. 2.

ID

ZDB-IMAGE-190723-2565

Antibodies

Source

Figures for Skvarca et al., 2019

Image

Figure Caption

Fig. 2.

UPHD25 treatment increases dedifferentiation during AKI. (A-C) Immunofluorescence co-stain of Vimentin (red; cytosolic) and Pax2a (green) in PT of age-matched 6-dpf no injury (A), 3 dpi gent-AKI+DMSO (B) and 3 dpi gent-AKI+UPHD25 (C) fish. (D) Quantification of Vimentin+ RTECs. Mean_{NoInjury+UPHD25}=0 (N=22) vs Mean_{Gent-AKI+DMSO}=8.00 (N=27) vs Mean_{Gent-AKI+UPHD25}=40.31 (N=29). Pax2a+ cells are marked with asterisks and Vimentin+ RTECs are marked with arrowheads. PT is outlined in white. Data pooled from three biological replicates are shown expressed as mean±s.e.m. One-way ANOVA: ****P<0.001. Scale bars: 20 μm.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.