ZFIN Image: Zhu et al., 2019, Figure 7

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Figure Caption

Figure 7

Ahi1 CRSIPR/Cas9-targeted embryos exhibited abnormal RGC axon projection patterns compared to WT embryos. (A) Fluorescent images of the optic nerve projection of WT and ahi1 CRSIPR/Cas9 targeted (ahi1mutant)-embryos at 4 dpf. Scale bar = 200 μm. (B) The statistical results of RGC axon length, abnormal crossing, and eye size of WT (n = 59) and ahi1 mutant (n = 46) embryos. (C) The ratios of embryos with normal retinal axon projection, abnormal middle crossing, and reduced axon elongation in WT and ahi1 mutant embryos. (D) The two-dimensional scatter diagram for the eye area of each WT or ahi1 mutant embryos. The X-axis represents the length of OT (μm²), and the Y-axis represents the size of eyes (μm²). Error bars denote SEM. ***p < 0.0001.

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Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.