ZFIN Image: Zhu et al., 2019, Figure 4

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Figure 4

The ahi1 morpholino-injected embryos exhibited retinal ganglion cell (RGC) axon projection defects at 4 dpf. (A) The normal retinotectal projection pattern of WT or control morpholino (Control MO)-injected embryos and defective retinotectal projections in the ahi1 morpholino (ahi1 MO)-injected embryos. Scale bar: 200 μm. (B) The statistical results of the RGC axon length and abnormal middle crossing of WT (n = 106), Control MO- (n = 112), and ahi1 MO- (n = 266) injected embryos. (C) The statistical results of eye sizes of WT and ahi1 MO-injected embryos. (D) The ratios of embryos with normal retinal axon projection (Normal), abnormal middle crossing (Middle crossing), and reduced axon longation (Reduced elongation) in the WT, control MO-, and ahi1 MO-injected embryos. (E) The two-dimensional scatter diagram for eye size in each group. The X-axis represents the length of OT (μm²), and the Y-axis represents the size of eyes (μm²). Error bars denote SEM. ***p < 0.0001 was determined via Student’s t-test.

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Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.