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Fig. 6
Knockdown of Gad1 causes jaw defects visible at 3 dpf (A) wild-type; (B) gad1b morphant; (C,D) BHQ-gad1b-ccMO; (E,F) CyHQ-gad1b-ccMO. (C,E) BHQ- and CyHQ-gad1b-ccMO injected embryos raised in the dark exhibit morphological development comparable to wild-type embryos. (B, D, F). BHQ- and CyHQ-gad1b-ccMO injected embryos raised in the light exhibit abnormal development of the presumptive lower jaw (region denoted by bracket) comparable to embryos injected with gad1b MOs; region includes Meckel’s cartilage. Scale bar in (A) applies to all panels.
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Full text @ ACS Chem. Neurosci.