Image
|
Figure Caption
Fig. S2
Torin treated fish are developmentally delayed
mbp mRNA expression at 5 dpf as detected by whole mount in situ hybridization. Wildtype larvae treated with the mTOR signaling pathway inhibitor TORIN1 have delayed developmental progression and slightly reduced levels of mbp mRNA both in the CNS and PNS. Genotypes were determined by PCR after imaging. Scale bar = 50 μm.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Cell, 47, Meireles, A.M., Shen, K., Zoupi, L., Iyer, H., Bouchard, E.L., Williams, A., Talbot, W.S., The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex, 319-330.e5, Copyright (2018) with permission from Elsevier. Full text @ Dev. Cell