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Fig. 7
Thymuses of Tg(rag2:jdp2) fish are resistant to dexamethasone. (A) Representative fluorescent images of thymuses from 8-d-old stable transgenic zebrafish larvae exposed to dexamethasone (25 µg/ml) or DMSO control, from day 5 postfertilization (dpf). Bar, 0.1 mm. (B) Quantification of thymic fluorescence in 8-d-old stable transgenic zebrafish larvae exposed to 25 µg/ml dexamethasone or DMSO control from 5 dpf. Values are expressed as a percentage of thymic fluorescence in DMSO control treated zebrafish, and P values were calculated using two-tailed Student’s t test. Findings were validated in three independent experiments.