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Fig. 1
Triptolide treatment alleviated MTZ-induced oedema and proteinuria. (A,C) Quantification of the oedema ratio (n = 30) and severity of oedema. The embryos were treated with 100 μM MTZ from 84 hpf to 132 hpf. Triptolide pretreatment obviously reduced MTZ-induced oedema percentage and severity. (B) Representative figure shows the severity of oedema (arrowhead) from a dorsal view (B1) and side view (B2). (D) GFP Quantification using ELISA showing that triptolide pretreatment reduced the MTZ-induced proteinuria (n = 3). **P < 0.01. (On the basis of three triplicate tests).
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