Fig. S3
myo1D morpohlino knock-down elicits Left-Right asymmetry defects a-g, Morpholino knock-down of myo1D elicits laterality defects at the level of the heart and viscera. myo1D morphants present defects in cardiac jogging (g) and looping (a-c, g). a-c are frontal views of the cmlc2-expressing heart at 48 hpf, dorsal up. d-f, myo1D knock-down impairs the leftward looping of the gut as well as the lateralized development of the liver (yellow arrows) and pancreas (red arrows). Dorsal views of visceral organs highlighted by an endodermal sox17:GFP transgene. Anterior is up. Scale bars: 20 μm in a-c. 50 μm in d-f.