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Fig. 1
The cq34 mutants exhibit hyperbranching cranial and intersegmental blood vessels. (A,B,G,H) Bright‐filed micrographs of the cq34 mutant reveal a decreased head and thin trunk at 48 hpf, and a pericardial edema at 72 hpf. (C–F, I–L) Blood vessels are visualized using the Tg(kdrl:GFP) transgenic line. The cq34 mutants display ectopic branching (arrowheads) in the head and dorsal part of the trunk at 48 hpf, which become more severe at 72 hpf. The aberrant branching of CtAs (C′, D′, I′, J′) and dorsal cranial vasculature (C″, D″, I″, J″) can be observed clearly under higher magnification. Scale bars, 100 μm (A,B,G,H), 50 μm (C–F, I–L).
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