ZFIN Image: Liu et al., 2018, Fig. 2

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Figure Caption

Fig. 2

Morphological characteristics of shank3b^−/− larvae and adult zebrafish. a–b Abnormal morphological changes in shank3b^−/− and shank3b^+/− larvae at ~ 1 dpf, including severe developmental delay, eye melanin reduction (blue arrow), and tail bending (red arrow) (+/+, N = 60; +/−, N = 50; −/−, N = 50). c–d Normal morphology and body length of shank3b^+/+, shank3b^+/−, and shank3b^−/− larvae at 3 dpf (c) and adults (6 mpf, male) (d) (N = 20 for each genotype). e–f Significantly enlarged brain size (e) but normal brain weight (f) in adult male shank3b^−/− (6 mpf) compared to WT zebrafish (N = 30 for each genotype). *p < 0.05

Figure Data

Phenotype details

Acknowledgments

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