ZFIN Image: Sánchez-Iranzo et al., 2018, Fig. S11

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Figure Caption

Fig. S11

Genetic ablation of tbx5a-derived ventricular cardiomyocytes in individualized fish.

a tbx5a⁺ ventricular cardiomyocytes were genetically ablated in tbx5a:CreER^T2;vmhcl:loxP-tagBFP-loxP-mCherry-NTR double transgenic zebrafish. Recombination was induced by administration of 4- Hydroxytamoxifen (4-OHT). Fish were individualised, imaged at 4 days postfertilisation (dpf) and cell ablation was induced by administration of Metronidazole (Mtz) from 4 to 7 dpf. b,f Maximum projection of confocal z-stacks of 4 dpf embryos. c–e, g–i Hearts dissected from the same fish at 42 dpf. at, atrium; ba, bulbus arteriosus; v, ventricle. Scale bars, b, f 25 μm, c, g 100 μm

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