ZFIN Image: Sánchez-Iranzo et al., 2018, Fig. 10

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Fig. 10

Summary of the contribution of tbx5a-positive and -negative myocardium during heart development and regeneration. a Identification of tbx5a-expressing and tbx5a-derived cells in the zebrafish heart. Red, tbx5a⁺ cells; green, tbx5a-derived cells not expressing tbx5a; yellow, tbx5a-expressing cells derived from embryonic tbx5a⁺ cells. b Replacement of the embryonic first heart field myocardium with second heart field progenitors. Blue, ventricular cardiomyocytes; red, tbx5a-derived ventricular cardiomyocytes; dotted red, ablated tbx5a-derived ventricular cardiomyocytes. c Contribution of tbx5a-derived cells during heart regeneration in the zebrafish. Red, tbx5a⁺ cells; green, tbx5a-derived cells not expressing tbx5a; yellow, tbx5a-expressing cells derived from trabecular adult tbx5a⁺ cells. 4-OHT, 4-Hydroxytamoxifen; at, atrium; Mtz, Metronidazole; v,ventricle

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