ZFIN Image: Ojeda Naharros et al., 2017, Fig. S4

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Figure Caption

Fig. S4

Polarized trafficking of transmembrane proteins not targeted to cilium occurs normally in cc2d2a-/- PRs.

Retinal cryosections of 4 dpf (A-B) and 6 dpf (C-D) wild-type (wt) (A, C) and cc2d2a-/- (B, D) zebrafish, stained with an antibody against Cacna1fa (green), an L-type calcium channel that localizes to the synapse, and counterstained with DAPI (nuclei, blue) and BODIPY (outer segments and mitochondrial cluster, magenta). (A’-D’) Close-ups of the synaptic regions boxed in A-D. Cacna1fa (grey) in the mutant (B’ and D’) presents a similar localization at synapses as in wt (A’ and C’) at 4 and 6 dpf. Scale bars: 10 μm in all figures.

Acknowledgments

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