Fig. 7
RA modulates the spatial expression of meis3 in the vagal and foregut tissue domains. (A-B) Following DEAB treatment from 24 to 52 hpf (B), the expression area of meis3 in the vagal (vg) region (yellow arrow) and foregut tissue (white arrow) is diminished when compared with control larvae (A). (C-D) Following heat shock induction, dnRaraa-GFP+ (D) larval fish exhibit a reduced expression domain of meis3 along the foregut (arrowhead) and vagal region, when compared to heat shock controls. (E-F) Following RA incubation from 24 to 48 hpf (F), the hindbrain expression of meis3 was rostrally expanded (brackets), as well as the foregut (arrow), when compared with control larvae (E).
Reprinted from Developmental Biology, 433(1), Uribe, R.A., Hong, S.S., Bronner, M.E., Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells, 17-32, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.