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Fig. 1
Fer kinase is conserved throughout evolution and is expressed during zebrafish embryogenesis. The zebrafish homologue of Fer kinase is highly conserved throughout eukaryotic organisms and contains the same domains as the human version (A). The zebrafish homologue of the fer kinase gene is expressed ubiquitously during early developmental stages with more specific expression emerging between 24 and 72 hpf (not shown). At 24 hpf, fer expression is observed in the intermediate cell mass (ICM) and developing brain region (B), when compared to a fer anti-sense probe (C). Quantitative PCR shows fer expression is highest during early development and tapers off by 24 hpf to three to four-fold lower levels (D).