ZFIN Image: Lagendijk et al., 2017, Fig. s3

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Figure Caption

Fig. s3

Gross phenotypes in kdr/kdrl morphant and SL327 treated embryos (a) Venus expression (grey) from Tg(ve-cad:ve-cadTS) in the trunk of an un-injected control (uic) and a kdr/kdrl MO injected embryo at 3 dpf showing a loss of intersegmental vessels (ISVs) in the morphant (asterisks). Scale bar = 10μm. (b) Venus expression (grey) at 3 dpf from Tg(ve-cad:ve-cadTS) in 1%DMSO treated control and SL327 (4μM/1%DMSO) treated embryos. Treatment from 20 hpf till 3 dpf. SL327 treatment results in only mild intersegmental vessel defects (compared to kdr/kdrl knockdown (a)) recognized by thin ISVs (black arrowhead). Scale bar = 10μm.

Acknowledgments

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