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Fig. s10 ER-restricted OTG (Otg-ER) retains its activity
(A-F) Morphology (A-C, at 24 hpf) and expression pattern of a dorsal organizer marker chd (D-F, 6 hpf; animal pole view, dorsal is to the right) of control (A, 13/13, 100%; D, 10/10, 100%), OTG mRNA-injected (B, 20/21, 95%; E, 12/13, 92%), or an ER-restricted OTG-ER mRNA-injected (C, 22/24, 92%; F, 11/13, 85%) embryos. Similar to wild type OTG, OTG- ER causes dorsalization and expansion of chd expression domain.
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