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Fig. S1
Effect of triptolide on zebrafish larvae after 48 hours (3-5dpf) exposure. Magnified histological images at x400 of zebrafish larvae liver after water exposure to triptolide at the concentrations indicated. Three representative fish are presented for each dose. Note the presence of dose dependent increase in hepatocyte vacuolation (A), necrosis (with nuclei breaking down (B) and karyolysis (C)) and the presence of disarray (red lines). The latter two features are absent from the control group. Scale bar = 20µm.
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