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Fig. 2
NBQX Injections Cause Time-Dependent Spontaneous Proliferation in Undamaged Retinas
(A) Model illustrating effects of NBQX injections on MG proliferation.
(B and C) Wild-type eyes were injected with PBS (B) or 25 nmol NBQX (C) into one eye. Fish recovered for 72 hr after NBQX injections (B and C) before proliferation was measured. Representative images are small portions of entire retina. Scale bar, 100 μm.
(D) Proliferating cells were counted across whole sections by PCNA staining for pretreatment (n = 5 eyes analyzed), PBS injection (n = 19), and NBQX injection (n = 16). hpi, hours post injection. One-way ANOVA was used; error bars denote SD; ∗∗∗∗p < 0.0001.