ZFIN Image: Liu et al., 2017, Fig. 7

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Figure Caption

Fig. 7

Cell number reduction correlates with axis extension defects in stat3 mutant embryos.

(A-D) Confocal image of dorsal mesoderm expressing mGFP in WT (A), Mstat3 (B), MZstat3 (C) embryos, and MZstat3 embryos overexpressing Stat3-F (D) at 11 hpf (anterior to the top). Somite boundaries are outlined in green. Adaxial cells are outlined in orange. Green arrows show AP dimension of each somite. Adaxial cells and notochord cells aligning along the AP axis are numbered in yellow. (E-G) Quantification of the average somite AP dimension (E), number of notochord cells (F) and number of adaxial cells (G) between adjacent furrows of the first two somites. (H-K) Schema of AP extension of the notochord and presomitic mesoderm. st, somite; nt, notochord. **p<0.01, ****p<0.0001, error bars = SEM.

Figure Data

Phenotype details

Acknowledgments

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