ZFIN Image: Noack Watt et al., 2016, Fig. S5

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Figure Caption

Fig. S5

Proliferation within pharyngeal arches 1 & 2 is reduced.

(A-C) similar levels of pHH3 staining are present in control, polr1c^-/- and polr1d^-/- embryos at 24 hpf. (D-F) Proliferation at 36 hpf also occurs globally at broadly similar levels in controls and mutant embryos, but there differences in the number of pHH3+ cells within pharyngeal arches 1 and 2. (G-I) Magnified views of pharyngeal arches 1 and 2 (outlined). (J, K) Quantification of pHH3+ labeled cells illustrating no global overall decrease in mutants embryos compared to controls, but a significant decrease in the percentage of pHH3+ cells in pharyngeal arches 1 and 2 in polr1c mutant embryos. polr1d mutant embryos showed a similar level of proliferation as polr1c mutants. Scale bar = 100 μm. * = p < 0.01 and error bars represent 95% confidence intervals.

Figure Data

Phenotype details

Acknowledgments

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