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Fig. 6
OPCs are specified normally despite reduction in reticulospinal neurons.
A, Posterior region of 48-60hpf Tg(olig2:EGFP; sox10:mRFP). EGFP+ mRFP+ cells (OPCs) indicated by arrowheads. At 60hpf some OPCs have migrated dorsally. Scale bar: 20 μm. B-C, Similar number of OPCs in 448μm-long regions of the spinal cord between WT and mutants at 48hpf (B) and 60hpf (C). Data from N = 10 WT and N = 9 mutants (48hpf anterior and 60hpf posterior) and N = 18 WT and N = 20 mutants. Error bars indicate ± SD.
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