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Fig. 3
Gnathostome Sox8, Sox9, and Sox10 sequences inserted into Tol2 vectors can all promote melanogenesis in cls mutants. (A–E) 96 hpf zebrafish larvae. Expression of Drsox8 (A), Drsox9a (B), Drsox9b (C), XlSox9 (D), and XlSox10 (E) in cls mutants. (F) box and whisker plot indicating the number of melanophoresrescued. Whiskers represent standard error. Each dot above the positive whiskers represents individual data points of the first quartile. Sample sizes are indicated under each bar on the X-axis.
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Reprinted from Developmental Biology, 418(1), Lee, E.M., Yuan, T., Ballim, R.D., Nguyen, K., Kelsh, R.N., Medeiros, D.M., McCauley, D.W., Functional constraints on SoxE proteins in neural crest development: the importance of differential expression for evolution of protein activity, 166-78, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.