ZFIN Image: Deshwar et al., 2016, Fig. S4

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Fig. S4

Depletion of Mespab, Mespba or Mespbb does not affect cardiac formation. (A-H) myl7 expression in WT and mespaa^hsc11 null maternal zygotic mutant embryos at 48 hpf injected with morpholinos against mespab (B,F), mespba (C,G) or mespbb (D,H) compared to uninjected controls (A,E). (I) Percent of embryos displaying normal or reversed heart looping when deficient for different Mesp family members alone or when co-injected with morpholino resistant mRNA. (J-N) The four categories of southpaw (spw) expression observed in WT and mespaa^hsc11 null maternal zygotic mutant embryos at the 20-22 somite stage. (N) Percent of embryos displaying the different southpaw expression patterns in WT and mespaa^hsc11 null maternal zygotic mutant embryos.

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Acknowledgments

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Reprinted from Developmental Biology, 418(1), Deshwar, A.R., Onderisin, J.C., Aleksandrova, A., Yuan, X., Burrows, J.T., Scott, I.C., Mespaa can potently induce cardiac fates in zebrafish, 17-27, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.