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Fig. S1
Pro-cardiac activity of Mespaa maps to both N- and C-terminal portions of the protein. (A) Schematic comparing the protein sequence of all four zebrafish Mesp family members. (B) Schematic of various Mesp fusion and mutant constructs and the ability of these constructs when RNA was over-expressed to confer pro-cardiac activity to transplanted cells in the animal cap.
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Reprinted from Developmental Biology, 418(1), Deshwar, A.R., Onderisin, J.C., Aleksandrova, A., Yuan, X., Burrows, J.T., Scott, I.C., Mespaa can potently induce cardiac fates in zebrafish, 17-27, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.