ZFIN Image: Deshwar et al., 2016, Fig. 2

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Figure Caption

Fig. 2

Mespaa is required early in gastrulation for pro-cardiac activity but over-expressing cells do not exhibit unique cellular behaviors until after its completion. (A) Schematic outlining the strategy for exploring the temporal requirement for mespaa in pro-cardiac activity. (B) Percent of host embryos with GFP+ cells at 48 hpf after animal cap transplantation of ecr-mespaa-Δnls over-expressing cells with tebufenozide addition at different time points. Data are represented as means±SEM. (C-F) Time-lapse images of animal cap transplants of mespaa and mespab over-expressing cells together at different stages in development.

Acknowledgments

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Reprinted from Developmental Biology, 418(1), Deshwar, A.R., Onderisin, J.C., Aleksandrova, A., Yuan, X., Burrows, J.T., Scott, I.C., Mespaa can potently induce cardiac fates in zebrafish, 17-27, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.