ZFIN Image: Shen et al., 2015, Fig. 2

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Figure Caption

Fig. 2

Otic developmental defects in Msrb3 morphants. (A) Overall morphology of mismatched controls (In2Con, a; Ex2Con, c) and msrb3 morphants (In2MO, b; Ex2MO, d) at 60 hpf indicated otolith abnormalities. Otic vesicles were visualized at 60 hpf using DIC microscopy. Scale bars: 50 µm. Unlike mismatch control (e; k), msrb3 morphants had tiny otoliths (f, l), abnormal otolith numbers (g, m), fused otoliths (h, n), misplaced otoliths (i, o), small otoliths (j, p), shrunken inner ears, and malformed semicircular canals (f-g, l-p). (B,C) Quantitative analysis of otolith defects of In2MO and Ex2MO at different concentrations at 60 hpf. Relative number of fish with otic developmental defects. (D,E) Statistical analysis of otolith abnormalities in controls and msrb3 morphants. Error bars are s.d. ***P<0.0001.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Dev. Biol.