Image
|
Figure Caption
Fig. 5
Cartilage and pre-cartilage markers col2a1a and sox9a are absent at 24 h post-fertilization (hpf) in fgf3;fgf8a knockdown embryos. (A-H) Images of 24 hpf embryos labeled with (A-D) col2a1a and (E-H) sox9a riboprobe. Dorsal view with anterior to the left, arrowhead denotes the anterior limit of the notochord. (A and E) Wildtype, (B and F) fgf8a mutant, and (C and G) fgf3 morpholino embryos display normal expression of both col2a1a and sox9a. However, (D and H) fgf3 morpholino-injected fgf8a mutants lose the expression of both col2a1a and sox9a (asterisk). scale bar=20 µm.
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 415(2), McCarthy, N., Sidik, A., Bertrand, J.Y., Eberhart, J.K., An Fgf-Shh signaling hierarchy regulates early specification of the zebrafish skull, 261-77, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.