ZFIN Image: Gauron et al., 2016, Fig. 2

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Figure Caption

Fig. 2

The H₂O₂ levels are regulated at the degradation step. (A-C) HyPer imaging during gastrulation. The embryos were incubated in 1 mM H₂O₂ and the HyPer signal was measured prior to incubation and 15 min after the addition of H₂O₂. Exogenous H₂O₂ enhanced the H₂O₂ signal in the tissues with high endogenous H₂O₂ levels (region x), but has a minimal, if any, effect on cells without H₂O₂ (region y). n=3; representative lateral views are shown. (D) Superoxide dismutase (SOD) activity (E) and Catalase (CAT) activity during development. Legends: 75% epi=gastrulation, 8 som=somitogenesis. The error bars represent the standard error of the mean (SEM) (*p<0.05; ***p<0.001).

Acknowledgments

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Reprinted from Developmental Biology, 414(2), Gauron, C., Meda, F., Dupont, E., Albadri, S., Quenech'Du, N., Ipendey, E., Volovitch, M., Del Bene, F., Joliot, A., Rampon, C., Vriz, S., Hydrogen peroxide (H2O2) controls axon pathfinding during zebrafish development, 133-41, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.