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Fig. 4
EEPD1 depletion in zebrafish embryos causes genome instability with or exogenous replication stress induced by 4 hr treatment with 5 mM HU. (A) Representative photomicrographs of somite nuclei in zebrafish embryos stained with DAPI. Arrows indicate micronuclei. (B) Percentage of somite nuclei displaying micronuclei. Values are averages (±SD) for 6-16 embryos per condition, 115-421 nuclei scored per embryo. *** indicates P ≤ 0.0001, t-tests.
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