Image
|
Figure Caption
Fig. S1
Expression of insulin and insulin receptors during development. (A-B) real-time PCR analysis of insulin a (insa), insulin receptor a (insra) and insulin receptor b (insrb) in embryos. n=3 for each time point. Inset graph shows magnified detail of circled region. (C-D) fluorescent in situ hybridization indicating the expression of insra + insrb (red) in pancreatic tissues, including the islet β (ins:CFP-NTRM in C, green) and α cells (gcga:GFP in D, green).
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Developmental Biology, 409(2), Ye, L., Robertson, M.A., Mastracci, T.L., Anderson, R.M., An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration, 354-69, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.