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Fig. S4
Time-course analysis of metastasis of control melanoma cells. Approximately 500 melanoma cells cultured on rigid dish were injected into the yolk sac of zebrafish and the tumor progression were monitored every 24 hr. Representative images from a fish were acquired from 0 dpi to 5 dpi. Arrows indicate primary tumors, arrowheads indicate disseminated tumor foci or tumor foci aggregates. Color code: zebrafish blood vessels are green, and melanoma cells are red. Scale bars, 500 µm.
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