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Fig. S1
. Examples of wnt11 derived mutants. (A–B) Confocal images of a single focal plan of WGA staining (gray) of Wnt/PCP mutant craniofacial cartilage elements at 4 dpf. Nuclei were labeled with DAPI (blue). Scale bar = 20 µm. (A) A wnt11 embryo with a cyclopic index of 2 demonstrating while the cartilage elements are deformed, chondrocytes are still able to elongate. (B) Confocal images of a single focal plan of a wnt5b; wnt11 double mutant demonstrating the loss of chondrocyte elongation and stacking similar to the wnt5b single mutant.
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Reprinted from Mechanisms of Development, 138 Pt 3, Sisson, B.E., Dale, R.M., Mui, S.R., Topczewska, J.M., Topczewski, J., A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis, 279-90, Copyright (2015) with permission from Elsevier. Full text @ Mech. Dev.