Fig. 5
Knockdown of slc26a2 induces semicircular canal defects in larval zebrafish.
(A) Changes in semicircular canal morphology and cilia size (scale bars = 30 µm). (B) Changes of neuromasts numbers and hair cell numbers in lateral line (scale bars = 20 µm). (C, D) Changes of cilia numbers in the inner ear (scale bars = 20 µm). (D) Statistical analysis of the ciliary bundles in the inner ear in different types of embryos at 120hpf, including wild type(WT), mismatch-MO control, S2-SP1 MO and Rescue. (E) Statistical analysis of the L1-8 neuromasts numbers in the posterior lateral line in different types of embryos at 120hpf, including WT, Mis-con, S2-SP1 and Rescue. (F) Statistical analysis of the hair cells numbers per neuromast in different types of embryos at 120hpf, including WT, Miscon, S2-SP1 and Rescue. ***P<0.001.