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Fig. S5 The initiation of nkx6.1 expression is independent of Notch signaling. A–D Fluorescent WISH showing a drastic increase in the pancreatic dorsal bud of ascl1b expression in the mind bomb (mib -/- ) mutants while nkx6.1 expression is not affected at 13 hpf. E, F Fluorescent WISH showing that the pancreatic expression of nkx6.1 in the ventral bud is not perturbed at 34 hpf in mib -/- mutants. The ventral (A, B, E, F) or lateral (C, D) views represent confocal projection images with the anterior to the left. Scale bars =40 µM. NS nervous system.
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Full text @ BMC Biol.