ZFIN Image: Helker et al., 2015, Fig. 1

Image

Figure Caption

Fig. 1 Angioblast migration to the midline is not regulated by Vegf.

(A–F) Schematic (A) and confocal (B–F) in vivo time-lapse imaging of angioblasts (green) and their migration in a Tg(fli1a:EGFP)^y1 embryo, injected with H2B-mCherry mRNA (purple, all nuclei), dorsal views at indicated time points. Arrows indicate the initial migration to the midline, and the coalescing into the dorsal aorta (DA). (G–J) Loss of Vegf-signaling components by vegfaa/vegfab double morpholino (MO) injection (H) or in vegf receptor 2 (kdrl) mutants (J) does not affect angioblast migration. Confocal projections of Tg(fli1a:EGFP)^y1 embryos in dorsal views at 17 hpf. For each condition, n > 15.

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Acknowledgments

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