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Fig. 5 Sustained fibroblast growth factor (FGF) signaling is required for dbx1b expression. (A-D) Eight-hour treatment of embryos with the FGF receptor antagonist SU5402 abolished dbx1b expression, however expression began to return 12 hours after treatment. (E-H) Similar results were seen when FGF receptor blockade was initiated after dbx1b expression began. Generation of Elav3l-positive habenular cells resumed following drug washout at both early and late time points (D, H). Scale bars are 50 μm.
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