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Fig. 2
Anterior and posterior semicircular canal cristae are lost in jag1b-/- mutants. (A) High resolution EGFP expression patterns in the otic vesicle of jag1b+/- embryos. Images taken at 30hpf-48hpf are dorsolateral views. Other images are lateral views. (B,C) Confocal imaging (B) and phalloidin staining (C) of jag1b+/- and jag1b-/- embryos at 48hpf (B) and 72hpf (C). (B) Dorsolateral views. (C) Lateral views. Anterior towards the left and dorsal upwards. Scale bars: 50µm. AC, anterior crista; LC, lateral crista; PC, posterior crista. Arrows and arrowheads indicate sensory crista regions.
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